Found inside â Page 7830Ascalone V , et al . J Chromatogr 1993 cetirizine and ebastine : a crossover , double - blind study , Drugs and Pregnancy Study Group . ... N Engl J Med 1994 Oct 13 ; 331 ( 15 ) : 1020 Purkinje fibers more than acrivastine . To make ⦠Acrivastine vs Fexofenadine and Cetirizine: Because of the rapid onset of action, compared to cetirizine and fexofenadine, acrivastine should be used in emergency settings when an anti-allergic response is needed. Before taking cetirizine. As for Loratadine, it also works by blocking histamine in our body. [Oral second generation antihistamines in allergic rhinitis]. Acrivastine isn't recommended for people over 65 years old because very little research on the medicine has been done in this age group Contact Us. Acrivastine Impurity C â Varanous Labs. Safety and efficacy of desloratadine in subjects with seasonal allergic rhinitis or chronic urticaria: results of four postmarketing surveillance studies. Zyrtec (Cetirizine) For Cats - Cat-Worl . Found insideIf he is under 18 years, an oral or topical antihistamine could be recommended, bearing in mind that he is sitting ... You know that he is not taking any other medicines, so you could recommend acrivastine, loratadine or cetirizine but ... Found inside â Page 95The data on acrivastine is currently lacking and further information on its cardiac safety is urgently needed. ... the use of acrivastine has been related to cardiac death or arrhythmias typically caused by terfenadine. Can be used as content for research and analysis. It gets to work faster than cetirizine and loratadine tablets and capsules. 10-25% of population worldwide is affected by AR. Cetirizine (Zyrtec) and loratadine (Claritin) are non-sedating antihistamines used to treat symptoms of allergic reaction such as symptoms of seasonal hay fever (allergic rhinitis) such as sneezing, runny nose, red/watery/ itchy eyes, hives, and allergic skin rash. [loratadine 63% vs. cetirizine 45%, placebo 13%]. Cellular inflammatory responses and mediator release during early ⦠Generally, they are given in the same dosage of 10mg and under different brand names and they will essentially all have the same effect. H2 blockers refer to compounds that inhibit the activity of H2 histamine receptors. For people with kidney or liver problems the recommended dose is 5 mg a day. Epub 2005 Jun 13. Do not take this medication if you are breast-feeding a baby. Clinical studies sponsored by the manufacturer have shown that ⦠Thank. ⦠Answered by Dr. Mark Loury: Yes: The two are compatible. Excipients. Non-sedating antihistamines such as acrivastine cause less sedation and psychomotor impairment than the older antihistamines, but can still occur; sedation is generally minimal. MeSH Short courses of oral cortisone or steroids are taken for short periods (one to three days) to settle more severe ⦠Adult dose . Cetirizine is not suitable for children under 2 years of age. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. This book presents the latest scientific knowledge on the role of pollens in triggering respiratory allergies and offers up-to-date guidance on the diagnosis, treatment, and prevention of pollen allergy. Acrivastine; Bilastine; Cetirizine; Desloratadine; Fexofenadine; Levocetirizine; Loratadine; Mizolastine; Rupatadine; Sitemap. The recommended dosage is 5 mg once per day in the evening. Acrivastine - LiverTox - NCBI Bookshelf. Plot No. This book presents a concise summary of relevant scientific and mechanistic information that can aid the use of excipients in formulation design and drug delivery applications. Loratadine is an antihistamine that effectively treats allergic-type reactions such as hay fever and is unlikely to cause drowsiness. Building on the success of the 14 previous editions, this remarkable reference has been extensively reorganized and expanded and now comprises almost 1,500 individual drug articles providing the most complete coverage of adverse reactions ... Sedating antihistamines such as Chlorphenamine(benadryl) or Hydroxyzine are used at night to get urticaria control. Roberta Fruttero. "is it safe to take zyrtec (cetirizine) and phenylephrine together?" However, if your phenylephrine is in another antihistamine product ulyou should no... Read More . As the name suggests, the drug combats histamine, a natural chemical in the body. They are used orally and some of them can be given by local application to the nose and eyes [2, 17]. Cetirizine is an antihistamine medication that can be used to treat allergic itching and other conditions in dogs. Acrivastine often also contains pseudoephedrine which you should avoid in dogs. there is another difference. Therefore, it is recommended that bilastine is taken at least one hour before and no sooner than two hours after a meal. Compared with loratadine, cetirizine was found to be approximately 3.5 times more likely to induce sedative effects. Concerning anti-pruritic effects, there appear no good research to compare the two antihistamine. Cetirizine was found to be superior to acrivastine and loratadine for the suppression of wheal and flare responses at 240, 360 min and 24 h (P < 0.05) and acrivastine was superior to the other two antihistamines for the suppression of flare response at 30 min (P < 0.05). Cetirizine, loratadine, or placebo in subjects with seasonal allergic rhinitis: effects after controlled ragweed pollen challenge in an environmental exposure unit. We offer this Site AS IS and without any warranties. Patients suffering from seasonal allergic rhinitis and urticaria ⦠1 thank. Allergy drug side effects, drug interactions, and toddler= or child-specific information depends on the type of medication. Double conventional doses of these non-sedating antihistamines such as Cetirizine(zyrtec), Loratadine(Claritin), Acrivastine and Fexofenadine may be needed to get symptom relief. When this route of administration is used, the dosage usually ranges ⦠Found inside â Page 180To our knowledge , no case of arrhythmogenic effect from acrivastine , cetirizine , levocabastine , or oxatomide has been published . The incidence of cardiotoxic adverse effects appears almost negligible compared to the great number of ... Found inside â Page 406Acrivastine may accumulate in the serum of patients with impaired renal function ( 4 ) . No specific toxic dose has been established . Cetirizine hydrochloride may cause drowsiness at therapeutic doses and does so reliably in overdose ... Ask your doctor if this would work for ⦠As do Loratadine and Desloratadine. This is because non-sedating antihistamines penetrate the blood brain barrier to a much lesser extent. Claritin is active in the body for at least 24 hours. Download PDF . Some of the examples for H1 blockers are acrivastine, buclizine, cetirizine, desloratadine, hydroxyzine, levocetirizine, maprotiline, promethazine, phenyltoloxamine, orphenadrine, tripelennamine, etc. Oral use. One study compared the reported instances of drowsiness and sedation experienced by users of four second generation antihistamines: loratadine (Claritin), fexofenadine (Allegra), acrivastine (Benadryl), and cetirizine (Zyrtecâs active ingredient). There are three kinds of common antihistamines that include cetirizine, loratadine and acrivastine. The other 3 groups received combination of the aforementioned an tihistamines with famotidine (40 mg, once a day). It is the second largest s⦠This volume provides a state-of-the-art account of the identification of new targets and the development of new therapies for these conditions. 12 Beside the clinical conditions ⦠CLARITIN REDITABS (loratadine rapidly-disintegrating tablets) mean AUC and C max were 11% and 6% greater than that of the CLARITIN Tablet values, respectively. Helps to alleviate symptoms such as sneezing, runny nose and itchy eyes. It's used to treat hay fever, conjunctivitis (red, itchy eyes), eczema and hives (urticaria). The National Health Service (NHS) is the publicly funded healthcare system in England, and one of the four National Health Service systems in the United Kingdom. Severity of interaction: Moderate Evidence for interaction: Theoretical. Zyrtec and Claritin are two popular antihistamines that can reduce allergy symptoms such as sneezing, itching, and rashes. Roberta Fruttero. Antihistamines or allergy medications, whether prescription or over-the-counter (OTc) are used to treat allergy conditions and symptoms, such as itchy, watery eyes, a runny nose, scratchy throat and a rash. Acrivastine: Acrivastine: Cetirizine: Cetirizine: Lortatadine: Ebastine: Loratadine: Mizolastine: Third Generation: Desloratadine: Desloratadine : Fexofenadine: Fexofenadine: Levocetirizine: Levocetirizine: Methods. Contains acrivastine â Benadryl Allergy Relief contains acrivastine, a non-sedating antihistamine which at the recommended dose does not cause drowsiness in the majority of people. Benadryl Allergy & Hayfever Acrivastine Tablets 12s. Cetirizine is a prescription approved by the U.S. Food and Drug Administration (), and over-the-counter antihistamine medication.This drug may be used as a treatment for annual or seasonal allergic and vasomotor rhinitis (inflammation of the membranes of the nose not caused by an allergy).This medication is also used as a treatment to provide relief of cold symptoms and ⦠J Allergy Clin Immunol. Double conventional doses of these non-sedating antihistamines such as Cetirizine(zyrtec), Loratadine(Claritin), Acrivastine and Fexofenadine may be needed to get symptom relief. Found insideA short - acting classic antihistamine may be added at night to a daily second- or third - generation ... once daily 400 mg twice daily 150 mg twice daily Diphenhydramine ( 2 ) Acrivastine ( 1 ) Cetirizine ( 1 ) Loratadine ( 1 ) ... Cetirizine was found to be superior to acrivastine and loratadine for the suppression of wheal and flare responses at 240, 360 min and 24 h (P < 0.05) and acrivastine ⦠Collected from the entire web and summarized to include only the most important parts of it. Bilastine is a new, well-tolerated, nonsedating H1 receptor antihistamine. F, ⦠New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more. Over 700 illustrations supplement this must-have resource. The overall incidence densities for sedation with loratadine, acrivastine, fexofenadine and cetirizine were 1.2, 4.4, 1.5 and 3.7 reports per 1000 patient-months of exposure, respectively. The dose is 1mg per pound body weight every 12 hours. 87848-99-5 | Acrivastine | C22H24N2O2. All rights reserved. Learn more about Zyrtec (cetirizine ⦠Acrivastine ⦠Double conventional doses of these non-sedating antihistamines such as Cetirizine(zyrtec), Loratadine(Claritin), Acrivastine and Fexofenadine may be needed to get symptom relief. Perfect for clinicians in primary and secondary care settings, this practical volume covers what is most useful in your daily practice, with a strong emphasis on disease diagnosis and management. Aprodine has 2.5mg of antihistamine which adds another 5mg a day totaling 30mg of antihistamine per day. Sedating antihistamines such as Chlorphenamine or Hydroxyzine are used at night to get urticaria control. Ciprandi G, Cirillo I, Vizzaccaro A, Civardi E, Barberi S, Allen M, Marseglia GL. In 2007, the US FDA made it available as an over-the-counter medication. It is the second largest s⦠Claritin is the brand name for the active drug called Loratadine. CERSI Excipients Browser - ACRIVASTINE⦠Acrivastine capsules that you buy from pharmacies and supermarkets can be taken by adults under the age of 65, and children aged 12 years and over. Alessandra Pagliara. Acrivastine. This medication was originally approved by the US FDA in 1996 as a prescription medicine. The decrease in cetirizine clearance in these elderly volunteers appeared to be related to their decreased renal ⦠Cetirizine (brand name – Zyrtec) belongs to a group of medicines called second-generation antihistamines which stop the effects of histamine, a naturally occurring substance. Acrivastine ⦠Int Immunopharmacol. This invaluable guide, endorsed by the UKMi and reflecting the extensive experience of the UK Renal Pharmacy Group, features drug monographs guiding physicians in how to prescribe, prepare, and administer drugs to patients with different ... Cetirizine is licensed for the relief of symptoms of chronic idiopathic urticaria at a dose of 10 mg daily in adults and young people aged over 12 years, 5 mg twice daily in children aged 6â12 years, and 2.5 mg twice daily in children aged 2â6 years. Cetirizine â peak plasma levels of cetirizine and loratadine are reached in about 1 hour; they have a long elimination half-life and are long acting, requiring only once-daily dosage. ... Acrivastine: This is a antihistamine. Acrivastine â a rapid onset of action and a short half-life, requiring more frequent dosing than cetirizine or loratadine, but it may be useful to provide rapid relief. During the study, each patient received either one tablet of placebo, 10 mg of cetirizine or 10 mg of loratadine daily. bilastine vs cetirizine depakote. It's also used for reactions to The second-generation antihistamines include acrivastine, astemizole, azelastine, carebastine, cetirizine, ebastine, loratadine, mizolastine, and terfenadine. Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. But theyâll give you much-needed relief for a runny or congested nose. Antihistamines work by preventing the actions of histamine. The study lasted 7 weeks, including 1 for pretreatment, 4 for treatment and 2 posttreatment (washout). It works by blocking the action of histamine, a neurotransmitter in the body that causes allergic symptoms. This in turn prevents the release of additional allergy chemicals and blood supply to the area, providing relief from the typical allergy symptoms. Benadryl allergy relief capsules contain the active ingredient acrivastine, which is a type of medicine called a non-sedating antihistamine NHS description: Benadryl contains the active ingredient acrivastine. Manufacturer makes no recommendation. Clin Drug Investig. Bottom Line â Levocetirizine vs Cetirizine. Manufacturer makes no recommendation. Found inside â Page 271Chlorpheniramine Cetirizine vs. Hydroxyzine Cetirizine vs. Hydroxyzine Loratadine vs. ... also markedly less sedation with doxepin Reference 22 23 24 25 26 27 Continued Table 20-2 Continued Acrivastine vs. Clemastine Acrivastine vs. Extra attention to vacuuming of the car, furniture, and especially the dogâs or catâs bed, will help keep the allergens lower. Intravenous cetirizine was also associated with a lower rate of return to the emergency department (6% vs 14%) and time between treatment and discharge (1.7 vs 2.1 hours). Acrivastine is a non-sedating antihistamine, which works by blocking histamine H1 receptors, which cause allergic symptoms. Careers. Found inside â Page 144Compounds available are: â acrivastine â cetirizine â loratadine. All are of equal efficacy. â¡ Acrivastine has a rapid onset of action and a short half-life, necessitating more frequent dosing than cetirizine or loratadine, ... The recommended dose for children 11 years and more is 5 to 10 mg a day. Cetirizine is an over-the-counter antihistamine used for allergies. The neurotransmitter acts on histamine receptors, ultimately, leading to a chain reaction which usually results in allergic symptoms. Non-drowsy Benadryl. Cetirizine was found to be superior to acrivastine and loratadine for the suppression of wheal and flare responses at 240, 360 min and 24 h (P < 0.05) and acrivastine was superior to the other two antihistamines for the suppression of flare response at 30 min (P < 0.05). Avoidance is the most straightforward strategy for managing dog or cat allergies. Acrivastine is effective and well tolerated over prolonged periods (up to 52 days) for the treatment of seasonal allergic rhinitis. Delivery's free, though you'll have to pay if ordering other non-offer items. Read more. We conducted a systematic search of the MEDLINE medical literature database for articles published between 1950 and May 2009 using the search terms ⦠I take 10mg at night then another 15mg (1 1/2 pills) in the morning. Activated mast cells release pro-inflammatory cytokines such as IL-1, IL-6 and TNF-α as well as bronchoconstrictor mediators such as histamine, prostaglandin-D2 and leukotriene-C4. Your GP can also prescribe other non-sedating antihistamines, such as fexofenadine ⦠Compared with loratadine [odds for sedation were 2.79 (95% CI ratio (OR) 1], the ORs 1.69â4.58) for acrivastine, 0.63 (0.36â1.11) for fexofenadine and 3.53 (2.07â5.42) for cetirizine. Before taking cetirizine. Giulia Caron. Would you like email updates of new search results? Cetirizine can be prescribed for you by a doctor or dentist, or you can buy it without a prescription at pharmacies and other retail outlets. If you are one of those persons who frequently experiences hypersensitivity reactions, otherwise known as allergies, then you may be a regular user of antihistamines (anti-allergy drugs). I note that the WIkipedia article about Loratadine suggests that it may not be particularly effective at non-sedating doses. Another factor in H1A safety is the dependence on drugâdrug interference at the level of metabolism, the lack of significant hepatic metabolism probably contributes to the freedom from significant cardiotoxic potential shown by some other second generation H1A, such as desloratadine, cetirizine, levocetirizine, and acrivastine. The aim of this double-blind study was to evaluate the effectiveness of cetirizine and loratadine versus placebo in patients with allergic rhinitis. Can be used as content for research and analysis. J Invest Allerg Clin Immunol. The excipients listed in the manufacturerâs information are as follows:. Also, you should not take this antihistamine if you are pregnant without first consulting your healthcare professional. Found inside â Page 6Acrivastine b. Cetirizine c. Fexofenadine d. Loratadine Answer A is correct. Acrivastine should be avoided in patients with severe hypertension or coronary artery disease. Cetirizine, fexofenadine, and loratidine do not have ... The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Subscribe to MedHelp's free newsletter for Community Support, Experience, and Guidance. Cetirizine exhibits linear kinetics over the range of 5 to 60 mg. Special populations. Alimemazine is predicted to decrease the effects of betahistine. FDA pregnancy category B. Cetirizine, loratadine and chlorpheniramine are just a few examples of common antihistamines which work well for allergies. 2009 May;31(5):921-44. doi: 10.1016/j.clinthera.2009.05.017. For statistical analysis we used the Mantel-Haenszel method and chi-square test. These are: acrivastine, cetirizine, levocetirizine (pronounced lee-vo-se-ti-ri-zeen; an isomer of cetirizine), fexofenadine, loratadine, desloratadine (pronounced des-lor-ra-ta-deen; a major metabolite of loratadine), mizolastine and terfenadine. It is a second-generation antihistamine (brand name – Zyrtec), commonly used to treat cold symptoms, nasal congestion, hives, or severe allergies. It is taken by mouth. Sometimes, when the body is exposed to a foreign substance (an allergen) it reacts by releasing its histamine stores from the mast cells. 2/10 in overall patient satisfaction Acrivastine is available in capsule form, and is sometimes known as Benadryl. This second-generation antihistamine is used to treat swelling and itching caused by chronic urticaria. It was concluded that both antihistamines were significantly superior to placebo and that cetirizine performed better in comparison to loratadine versus placebo, although not as statistically significant. The nasal cytology was analyzed on days 1 and 29. It is a Pregnancy Category B drug, which means it is not expected to negatively affect an unborn baby. Acrivastine is Others (ebastine, fexofenadine, loratadine and terfenadine) did not have significant effects after recommended doses but had at least measurable effects after doses that were twice as high. The only drawback of this medication is that is causes drowsiness in ~5-10% of people and therefore is NOT marketed or labeled as non-drowsy. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Cetirizine FTW: Most allergists would recommend cetirizine. Unable to load your collection due to an error, Unable to load your delegates due to an error. Pharmacy Law and Ethics General Pharmaceutical Council Guidance Royal Pharmaceutical Society Guidance PSNI Code of Ethics, Standards and Guidance Medicines, Ethics and Practice Prescriptions Controlled Drugs Supplementary and Independent ⦠Compare Benadryl vs Cetirizine ⦠This book focuses on the impact of pregnancy on drug disposition and also includes coverage of treatments for diseases of specific body systems, as well as essential content on dosing and efficacy. It's used to treat conditions such as hay fever, conjunctivitis and eczema. Obat ini bekerja dengan cara memblokir histamin, yaitu senyawa yang meningkat jumlahnya dan ⦠Since it is non-drowsy it will do nothing to help you fall asleep faster or prevent you from waking up at 1 or 2am. Sedating antihistamines such as Chlorphenamine(benadryl) or Hydroxyzine are used at night to get urticaria control. Benadryl Allergy Relief contains acrivastine which starts to work in just 15 minutes and lasts up to 8 hours.The capsules provide relief from hayfever and dust, pet and skin allergy symptoms, including itchy and runny nose, sneezing, watery eyes and hives.Directions for use: Suitable for adults and children between 12 - 65 years old. It should not be confused with Benadryl Once a Day which has cetirizine as the active ingredient and is also sold by McNeil in the UK, nor with the American Benadryl, which uses diphenhydramine as its active ingredient. I, also, take Aprodine twice a day. SMPDB. Oral/intranasal H1-antihistamine, decongestants, leukotriene receptor antagonists, intranasal corticosteroids are the pillars in the management of AR.Materials and methods: Seventy patients with allergic rhinitis participated in a prospective, randomized, double ⦠And itâs more effective if you start taking antihistamines before the hay fever season. Cetirizine can be prescribed for you by a doctor or dentist, or you can buy it without a prescription at pharmacies and other retail outlets. So it just depends on whether a person prefers a particular brand or will buy a cheaper generic. Clin Ther. Connect by text or ⦠Although drowsiness with cetirizine is uncommon, cetirizine... View more. Ibuprofen vs Aleve (Naproxen) – Which Is Better For Toothache? SynZeal Research Pvt Ltd. Whether you are preparing for the new sleep medicine fellowship examination, or simply want to offer your patients today's best care, this is the one resource to use! Cetirizine was found to be superior to acrivastine and loratadine for the suppression of wheal and flare responses at 240, 360 min and 24 h (P < 0.05) and acrivastine was superior to the other two antihistamines for the suppression of flare response at 30 min (P < 0.05). Allergy due to any excipient is possible but polyethylene glycol is of particular importance. Atkins PC, Zweiman B, Moskovitz A, et al. © Copyright 2021 YOUR HEALTH REMEDY. Found inside â Page 1185We calculated nonadjusted and age and sex adjusted odds ratios for drowsiness or sedation for fexofenadine , cetirizine , and acrivastine using loratadine as baseline . 5 IL 0 Injury Cough Respiratory tract infection Asthma , wheezing ... Drugs. Firstly, is important to know exactly what Claritin is, and then how the drug will work within the dogâs system. Tell your healthcare provider about all the medications you take, especially: This third-generation non-sedating antihistamine can pass into breast milk and may negatively affect the baby. ALC-0315 = ((4-hydroxybutyl) azanediyl)bis (hexane ⦠Levocetirizine (brand name â Xyzal) is a potent third generation antihistamine that has the ability to inhibit cutaneous histamine-induced itching and the wheal and flare reaction. For statistical analysis we used the Mantel-Haenszel method and chi-square test. Found inside â Page 83Acrivastine Acrivastine is a non-sedating antihistamine that doesn't usually cause any severe side eÌects, ... experience drowsiness and blurred vision, so check that your reaction times are normal before operating machinery or driving. 2001. Allergy and cross-sensitivity . ⦠Loratadine, fexofenadine, desloratidine, rupatadine and bilastine are the least-sedating antihistamines and, presently, loratadine, fexofenadine and desloratidine are the sanctioned choices for pilots, truck drivers and others who perform complex tasks like operating heavy machinery vs. cetirizine which is a low-sedating antihistamine [6, 9, 40]. Acrivastine is an antihistamine medicine that relieves the symptoms of allergies. Collected from the entire web and summarized to include only the most important parts of it. 2- Chlorpheniramine, the dose is 4-8mg every 8-12 hours (max dose 0.5mg/kg). Prevention and treatment information (HHS). Contra-indications. Acrivastine. 8600 Rockville Pike 1999; 9:351â355. In medical settings, diphenhydramine will sometimes be injected, either intravenously, into muscle, or under the skin (although subcutaneous injection is not recommended in humans). Acrivastine - Wikipedia. Short courses of oral cortisone or steroids are taken for short periods (one to three ⦠It doesnât prevent the release of the histamine but prevents histamine binding to its receptors. Cetirizine: a review of its use in allergic disorders. Both acrivastine and cetirizine treat allergy symptoms from hayfever and skin rashes. These symptoms include sneezing, runny nose, itchy and red skin, itchy or watery eyes, and itchy throat or nose. Sarah has made her choice after talking about the uses, side effects, and contraindications of both acrivastine and cetirizine with the pharmacist. Cetirizine has a significant bronchodilatory effect in patients with mild-to-moderate asthma and can be used to treat concomitant conditions (e.g., allergic rhinitis) without concern that it will interfere with the bronchodilatory effect of albuterol or cause worsening of asthma by itself. The manufacturerâs information states that a hypersensitivity to any of the excipients is a contraindication to the vaccine use.. Excipients present. The typical daily dose of Claritin for adults and children who are 6 years and older is 10 mg per day. A better option would be: 1- Diphenhydramine which here in the US also goes by Benadryl. Found inside â Page 136Overdose patients should be carefully monitored as long as the QT interval is prolonged or arrhythmias are present. In some cases, this has been up to 6 days. Cetirizine (Reactine) Cetirizine is the carboxylic acid metabolite of the ... The nasal cytology was analyzed on days 1 and 29. Histamine is stored in mast cells which can be found in almost all tissues of the body. Should be ok to take with phenylephrine. Benadryl allergy relief capsules contain the active ingredient acrivastine, which is a type of medicine called a non-sedating antihistamine.
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