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Since the discovery of the first miRNA in 1993 and another miRNA let-7 7 years later (Lee et al., 1993; Reinhart et al., 2000; Di Leva et al., 2014), people’s understanding of miRNA has been deepened for more than two decades, and the potential therapeutic effects of miRNA have been explored. Journal Abbreviation Database (Journal Abbr.com) Frontiers in cell and developmental biology Abbreviation. Rev. Eur. doi: 10.1093/abbs/gmx104, Hata, A. In this book, we present the state of the art of S. aureus virulence mechanisms and antibiotic-resistance profiles, providing an unprecedented and comprehensive collection of up-to-date research about the evolution, dissemination, and ... Subramanian, A., and Schilling, T. F. (2014). (2018). 6:330. doi: 10.3389/fphys.2015.00330, Thankam, F. G., Boosani, C. S., Dilisio, M. F., and Agrawal, D. K. (2018). Psychiatry Series (Berlin), Maongraphs/ National Cancer Institute (Bethesda. (2015). Nat. The high-mobility AT-hook 2 (HMGA2) mRNA transcript, involved in many cellular processes, contains seven complementary sites for let-7 binding in its 3′ -UTR and is known for its regulatory role in stem cell self-renewal and differentiation along with oncogenesis (Hammond and Sharpless, 2008). I graduated with a B.S. 217:e20190103. Trends in Microbiology publishes commissioned, peer-reviewed articles across all aspects of microbiology from cell biology to genetics and evolution. miRNA can inhibit protein synthesis by binding to COL5A1 3′-UTR to regulate target mRNA stability and/or translation efficiency (Garzon et al., 2009). Fritz, J. V., Heintz-Buschart, A., Ghosal, A., Wampach, L., Etheridge, A., Galas, D., et al. 93, 1955–1986. (2003). Biochem 454, 97–109. MicroRNAs in development and disease. Biol. doi: 10.1002/jcp.27486. Selected peer-reviewed full text paper from the International Conference on the Frontiers in Molecular Sciences (ICFMS 2020) Selected, peer-reviewed papers from the International Conference on the Frontier in Molecular Sciences (ICFMS), ... 60, 167–179. Commun. The Nature Publishing Group (NPG) is owned by the German publishing house Holtzbrinck Publishing Group, which is also the partial owner of Frontiers. J. Exp. doi: 10.1038/nature02871, Ambros, V., Bartel, B., Bartel, D. P., Burge, C. B., Carrington, J. C., Chen, X., et al. Biol. 5, 5–23. J. ». 116, 454–462. Tendons are located between muscles and bones and can cushion the pressure caused by the direct interaction between muscles and bones, thereby stabilizing the joints (Laurencin and Freeman, 2005; Thorpe and Screen, 2016). (2007). Cell differentiation versus cell death: extracellular glucose is a key determinant of cell fate following oxidative stress exposure. G doi: 10.1034/j.1600-0838.2000.010006312.x, Katzel, E. B., Wolenski, M., Loiselle, A. E., Basile, P., Flick, L. M., Langstein, H. N., et al. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. However, the basic cellular biology and pathology of tendons are still not fully understood, and the management of tendon injury remains a considerable challenge. Furthermore, TSPCs senescence may lead to defective self-renewal and altered fate (Zhou et al., 2010). J. Orthop. ISSN: 2296-634X (Electronic) 2296-634X (Linking) ISSN: 2296-634X (Online) Other Information: Frequency: Monthly Country: Switzerland Publisher: Lausanne : Frontiers Media S.A., [2013]-Website: The formation of new capillaries through angiogenesis is the key to tendon healing. Editor In Chief: Dr. Yahia Z Hamada, Professor of Chemistry and Biochemistry, Department of Natural and Mathematical Sciences, LeMoyne-Owen College, Memphis, USA. doi: 10.1111/j.1600-0838.2005.00439.x, Nichols, A. E. C., Best, K. T., and Loiselle, A. E. (2019). Frontiers in Cellular and Infection Microbiology is a leading specialty journal, publishing rigorously peer-reviewed research across all pathogenic microorganisms and their interaction with their hosts. (2002). Cell Death Dis. R (2009). C Frontiers in cell and developmental biology. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Hanski made seminal contributions to both empirical and theoretical metapopulation biology throughout his scientific career. doi: 10.1038/35002607, Rittié, L. (2017). Frontiers is based in Lausanne, Switzerland, with other offices in London, Madrid, Seattle and Brussels. doi: 10.3390/ijms12074315, Zhou, Z., Akinbiyi, T., Xu, L., Ramcharan, M., Leong, D. J., Ros, S. J., et al. They are attached to muscles and bones, and stabilize joints by cushioning the pressure caused by direct interaction between muscles and bones (Laurencin and Freeman, 2005; Thorpe and Screen, 2016). Which is the most effective rebuttal to this counterclaim? Mol. Ther. Hand Surg. (2017). Tendinopathy is a failed healing reaction, accompanied by haphazard proliferation of tendinocytes, intracellular abnormalities, destruction of collagen fibers, and subsequent increase in the non-collagen matrix (Longo et al., 2018). RNA polymerase III transcribes human microRNAs. 29, 684–693. J High glucose combined with oxidative stress lead to the up-regulation of miR28-5p which directly down-regulates the expression of p53 deacetylase sirtuin 3, leading to the increase of p53 acetylation level (Poulsen et al., 2014). A. The Cerebellum and Cognition pulls together a preeminent group of authors. The cerebellum has been previously considered as a highly complex structure involved only with motor control. According to the latest version of the microribonucleic acid database (miRBase) released in 2018, the human genome contains 1,917 annotated hairpin precursors and 2,654 mature sequences (Kozomara et al., 2019). Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma. (Shanghai) 49, 1015–1021. Philos. Gaut, L., and Duprez, D. (2016). doi: 10.1126/science.1149460, Vidigal, J. Biol. This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Ser. Int. Surg. M Frontiers in cell and developmental biology; Annual review of cell biology; Frontiers in Systems and Synthetic Biology. Field Chief Editor Prof. Yunde Zhao at the University of California is supported by an outstanding Editorial Board of international researchers. Orthop. Abbreviations used in this paper: . Cell Biol. Tendons connect the muscle abdomen of skeletal muscles to the bone, which transmits the force generated by the muscle abdomen contraction and pulls the bone into motion. Abbreviations for quotation according to ISO standard. Rho-associated coiled-coil protein kinase 1 (ROCK1) plays vital roles in many aspects including cell morphology, mitosis, motility, and even senescence (Julian and Olson, 2014; Guan et al., 2020). Sports Med. 34, 1777–1784.e1. J. Hum. doi: 10.1111/j.1600-0838.1997.tb00119.x, Posthumus, M., Schwellnus, M. P., and Collins, M. (2011). Since the discovery of miRNA in the 1990s, people’s understanding of miRNAs has been deepened (Lee et al., 1993; Di Leva et al., 2014), and its application has become more and more extensive. Sin. H EGR1 induces tenogenic differentiation of tendon stem cells and promotes rabbit rotator cuff repair. BioEssays : news and reviews in molecular, cellular and developmental biology Abbreviation 250, 393–413. doi: 10.1007/s00776-015-0709-5, Vasudevan, S., Tong, Y., and Steitz, J. (2020). This handbook provides basic facts regarding foodborne pathogenic microorganisms and natural toxins. Please miRNA regulates gene expression mainly by binding to mRNA, which plays an important role in cell growth, differentiation, proliferation and apoptosis (Vasudevan et al., 2007; Sayed and Abdellatif, 2011). The MyomiR network in skeletal muscle plasticity. Cell Differentiation and Development . Int. Sci. Frontiers in Drug Design and Discovery . Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration. The ISO4 abbreviation of Frontiers in Cell and Developmental Biology is Front. 12, 18436–18452. Polymorphisms within the COL5A1 3’-UTR that alters mRNA structure and the MIR608 gene are associated with Achilles tendinopathy. 38, 319–329. A., Watson, S. S., Murchison, N. D., Staverosky, J. The impact factor (IF) 2020 of Developmental Cell is 12.270, which is computed in 2021 as per it's definition.Developmental Cell IF is increased by a factor of 2.18 and approximate percentage change is 21.58% when compared to preceding year 2019, which shows a rising trend. *Correspondence: Shengnan Qin, qinqinsn@163.com; Liangliang Xu, xull-2016@gzucm.edu.cn, †These authors have contributed equally to this work and share first authorship, Front. The network analysis of genes associated with AMPK and TREM-1 signaling revealed miR-31-5p, miR-195-5p and other thirteen miRNAs might be interrelated with the pathogenesis of RCT injury patients (Thankam et al., 2019). S When Juan Carlos Izpisua Belmonte and his team at Salk made global news headlines last fall for developing a technique for growing human stem cells within a mouse embryo, it no doubt puzzled the . Molecular Biology, Biochemistry and Biophysics (Berlin) Mol Biol Cell: Molecular Biology of the Cell (Bethesda, MD) Mol Biol Evol: Molecular Biology and Evolution (Chicago, IL) Mol Biol Med: Molecular Biology and Medicine (London) Mol Biol Rep: Molecular Biology Reports (Dordrecht) Mol Biother: Molecular Biotherapy (Stoneham, MA) Mol Brain Res Because metabolism & physiology overlap, this unique book waves a tapetry uniting & blending the explanations to yield a thorough discussion of both. 23, 167–175. Founded in 1965, In Vitro Cellular & Developmental Biology - Plant is the only journal devoted solely to worldwide coverage of in vitro biology in plants. Tendon development and diseases. View all Biol. Articles, The Chinese University of Hong Kong, China, University of Maryland, Baltimore, United States, University of California, Davis, United States. However, the use of antibiotics faces the challenge of a low efficacy and contributes further to the emerging infection rate by antibiotic-resistant strains, emphasizing the need for new therapeutic strategies. As a long-term pressure-bearing tissue, tendons are easy to form a variety of acute and chronic injuries (Khan et al., 1999). Biol. Tendon injury and tendinopathy: healing and repair. Nat. Commun. Sports 7, 55–61. It is constantly cross-linked to form the specific spatial structure of the tendon (Gaut and Duprez, 2016). Abbreviation 2: Curr Opin Cell Biol. K Cell Physiol. Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity. Bulletin. 77, 204–214. The place where the tendon is inserted into the muscle is called the tendon joint, while the joint between the tendon and the bone is called the bone-tendon junction (O’Brien, 1997; Thorpe and Screen, 2016). Update and implications for clinical management. |, https://doi.org/10.3389/fcell.2021.687117, Creative Commons Attribution License (CC BY). Tendon is mainly composed of type I collagen (also known as collagen I, COL I), which contains a small amount of proteoglycans, glycoproteins and minor collagens (Voleti et al., 2012). Sci. In its 3′-untranslated region (3′-UTR), COL5A1 gene has a BstUI restriction fragment length polymorphisms, which is associated with achilles tendon pathology and more specifically, chronic achilles tendinopathy (Mokone et al., 2006). A wide range of miRNAs in tendon injury have been shown to play vital roles in maintaining and regulating its physiological function, as well as regulating the tenogenic differentiation potential of stem cells. Frontiers seminars take place on Tuesdays from 1-2pm via Zoom (unless otherwise noted). Opin. Mesenchymal stromal cell secretome: influencing therapeutic potential by cellular pre-conditioning. Promoting the aims of cell biologists world-wide, papers relating to structure and function - especially where the findings are seen in a whole cell context . doi: 10.1007/978-3-319-33943-6_1, Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., and Brown, R. A. A., and Ventura, A. Exerc. The impact score (IS), also denoted as Journal impact score (JIS), of an academic journal is a measure of the . Annu. Biol. Navigation mit Access Keys . Interrelation of immunity and tissue repair or regeneration. Acad. J. Med. Aged TSPCs showed decreased tenogenic differentiation capacity and upregulation of p16 which is a direct target of miR-217 (Han et al., 2017). What is the process of people learning the culture of their society group of answer choices? p16(INK4A) mediates age-related changes in mesenchymal stem cells derived from human dental pulp through the DNA damage and stress response. The impact score (IS) 2020 of Anatomy and Cell Biology is 1.07, which is computed in 2021 as per its definition.Anatomy and Cell Biology IS is decreased by a factor of 0.16 and approximate percentage change is -13.01% when compared to preceding year 2019, which shows a falling trend. MicroRNA genes are transcribed by RNA polymerase II. (2015b). Tendon injury is a common clinical condition occurring in certain populations, such as repeated tendon strains in athletes. J. This volume establishes the standard for those who need the latest and best information on the physiology of birds. (2019). Table 2. This book provides an understanding on a large variety of related topics in fish biology. The further development on molecular and cellular biology and ecology leads to assimilate the newer scientific knowledge in this area. Biology of tendon injury: healing, modeling and remodeling. Neurosci. Front. Development 136, 1351–1361. Pathol. In this view, when 'developmental biology' was founded after World War II, it was not just another word for embryology (Horder, 2010).Nor has it been simply an expanded version, although 'experimental embryology across the living world' used to come close, and the field has broadened in recent decades. TGFβ and FGF promote tendon progenitor fate and act downstream of muscle contraction to regulate tendon differentiation during chick limb development. What are the stages of cell differentiation? (1985) 113, 56–62. miR-135a modulates tendon stem/progenitor cell senescence via suppressing ROCK1. Studies have revealed that various environmental factors including temperature, humidity, and air . doi: 10.1097/00000658-195113340-00019, Wu, Y. F., Chen, C. H., Cao, Y., Avanessian, B., Wang, X. T., and Tang, J. Nature 431, 350–355. Just as neural crest cells migrate great distances through the embryo, my journey has taken me from a childhood in a distant land to a career as a biologist. The 2021 Edition of the Journal Citation Reports® (JCR) published by Clarivate Analytics provides a combination of impact and influence metrics from 2020 Web of Science source data. Physiol. Recent studies have established that HMGA2 overexpression protected hTSPCs against H2O2-induced loss of stemness through autophagy activation, while increased HMGA2 silencing by the miRNA let-7 could induce hTSPC impairments, and thus plays a critical role in tendon homeostasis and regeneration (Sun et al., 2020). 23, 4051–4060. Dev. Nature 403, 901–906. doi: 10.1038/nn.3113. doi: 10.1371/journal.pone.0168077, Thankam, F. G., Boosani, C. S., Dilisio, M. F., Gross, R. M., and Agrawal, D. K. (2019). 2015:281756. (2021). Among the tendon cells, tenoblasts and tenocytes accounts for about 90%, while the remaining 10% are mainly composed of chondrocytes, synovial cells, vascular endothelial cells and smooth muscle cells (Sharma and Maffulli, 2006; Wang, 2006). Sci. 7, 8462–8470. Tendon disease is one of the most common diagnoses of people engaged in sports professions, accounting for 30% of the total number of injuries diagnosed (Millar et al., 2021). miRNAs play an important role in inflammation, cell cycle regulation, stress response, cell growth, differentiation, proliferation, apoptosis and migration etc. All authors read and approved the final manuscript. Human tendon behaviour and adaptation, in vivo. AMPK, adenosine 5′-monophosphate-activated protein kinase; BMSCs, bone marrow mesenchymal stem cells; COL 1, Type I Collagen; COL5A1, collagen type V α-1 chain; CUGBP2, CUG triplet repeat-binding protein 2; EC, endothelial cell; ECM, Extracellular Matrix; EGR-1, early growth response-1; FGF2, Fibroblast Growth Factor 2; HMGA2, high-mobility AT-hook 2; hTSPCs, human tendon-derived stem/progenitor cells; IRS1, insulin receptor substrate 1; KLF6, krüppel-like factor 6; miRBase, Microribonucleic Acid Database; miRNA/miR, microRNA; mRNA, messenger RNA; MSCs, mesenchymal stem cells; Nox4, NADPH oxidase 4; PPI, peptidyl-prolyl isomerase; pre-miRNA, miRNA precursor; RCT, rotator cuff tendon; RISC, RNA-induced silencing complex; ROCK1, Rho-associated coiled-coil protein kinase 1; Scx, scleraxis; Smad3, SMAD family member 3; TDSCs, tendon-derived stem cells; TGF-β, transforming growth factor-β; TNC, tenascin-C; TNMD, tenomodulin; TOB1, transducer of ERBB2 1; TREM-1, triggering receptor expressed on myeloid cells-1; TSCs, tendon stem cells; Tsp-4, thrombospondin-4; TSPCs, tendon stem/progenitor cells; VEGFA, vascular endothelial growth factor-A; UTR, untranslated region. doi: 10.1002/jor.22869, Borchert, G. M., Lanier, W., and Davidson, B. L. (2006). It has been reported that inflammation is involved in the whole process of tissue repair, with both advantages and disadvantages (Eming et al., 2009). Pathol. Elife 3:e02372. (2016). (2013). Type I collagen (COL1), forming macromolecular networks, is the most abundant protein in the human body and provides strength and resiliency to tissues such as tendons, and ligaments (Rittié, 2017). J. Orthop. Science 318, 1931–1934. miR-135a which directly binded to the 3′-UTR of ROCK1, suppresses proliferation, migration and tenogenic differentiation of TSPCs (Chen et al., 2015b). Brucellosis, also known as undulant fever, Mediterranean fever, or Malta fever, is an important human disease in many parts of the world. Annu. Editorial policy. 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Frontier Science Series . Sports Med. Nat. Bone Joint Surg. Figure 1. miRNAs related to tenogenic differentiation. J. Endocrinol. Its high-caliber original research and reviews make it required reading for anyone who needs comprehensive coverage of the latest developments and state-of-the-art research in plant cell and . The role of Pin1 protein in aging of human tendon stem/progenitor cells. Xue, M., and Jackson, C. J. doi: 10.1016/j.yexcr.2016.08.018, Wang, J. H. (2006). Genomics 39, 219–226. Dev. Earth Sci. Cell Dev. Biotechnological production . Res. Front. This book is designed to enhance the mechanistic understanding of signaling molecules and will be an important resource for plant biologists in developing stress tolerant crops to achieve sustainability under changing environmental ... It is the standardised abbreviation to be used for abstracting, indexing and referencing purposes and meets all criteria of the ISO 4 standard for abbreviating names of scientific journals. Exosomes are rich in miRNAs, which act as important regulators of intercellular communication and play an irreplaceable role in inflammation, fibrogenesis, and tissue repair (Simeoli et al., 2017). 502, 276–282. Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Early growth response-1 (EGR-1) regulated specific differentiation of TSPCs into tenocytes and also induced the expression of tendon marker genes SCX, TNMD, TNC, and COL1 both in vitro and in vivo (Tao et al., 2015). 1627, 287–308. Frontiers in Physiologyis a leading journal in its field, publishing rigorously peer-reviewed research on the physiology of living systems, from the subcellular and molecular domains to the intact organism, and its interaction with the environment. miR-140-5p has been shown to delay the progression of human TSPCs senescence by targeting Pin1 which is a highly conserved peptidyl-prolyl isomerase (PPI) (Chen et al., 2015a). Physiol. Cell Chemical Biology: Cell Death Differ. (2017). doi: 10.1038/nature07228, Sharma, P., and Maffulli, N. (2005). Methods Mol. . Cell Dev. Scand. Fabbri, M., Paone, A., Calore, F., Galli, R., Gaudio, E., Santhanam, R., et al. 87, 187–202. Mech. TOB1 (Transducer of ERBB2, 1) is one of the TOB/B-cell translocation gene family. (2017). Metal-Organic Frameworks for Biomedical Applications is a comprehensive, authoritative reference that offers a substantial and complete treatment of published results that have yet to be critically reviewed. Is frontiers in cell and developmental biology a good journal? Trauma Surg. MicroRNA29a treatment improves early tendon injury. Q doi: 10.18632/aging.103771, Tao, X., Liu, J., Chen, L., Zhou, Y., and Tang, K. (2015). In adults, apoptosis is used to rid the body of cells that have been damaged beyond repair. Tau misfolding and assembly is linked to a number of neurodegenerative diseases collectively described as tauopathies, including Alzheimer's disease (AD) and Parkinson's disease. (2015). Antibiotic prophylaxis is currently recommended in high-risk infective endocarditis patients. J. Inflamm. Histological and biomechanical observations of the rabbit patellar tendon after removal of its central one-third. doi: 10.1038/gt.2015.97, Xiong, B., Rui, Y., Zhang, M., Shi, K., Jia, S., Tian, T., et al. In my spare time, I enjoy hiking, reading, and running. J. . 35, 2–10. Clustered miRNAs and their role in biological functions and diseases. Abbreviation: Front Cell Dev Biol.
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